aDepartment of Genomic Medicine, University of Cambridge, Cambridge, UK

bEarly Cancer Institute, Department of Oncology, University of Cambridge, Cambridge, UK

cSir Jeffrey Cheah Sunway Medical School, Faculty of Medical and Life Sciences, Sunway University, Sunway City, Malaysia

dGenomics England, London, UK

eLifebit Biotech, London, UK

fCancer Sciences Academic Unit, University of Southampton, Southampton, UK

gThe Clatterbridge Cancer Centre, Wirral, UK

hDepartment of Molecular and Clinical Cancer, Medicine, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK

iDivision of Oncology & Pathology, Department of Clinical Sciences, Lund University, Lund, Sweden

jBreast Unit, Royal Marsden Hospital and Institute of Cancer Research, London, UK

kNIHR Institute of Cancer Research BRC, London, UK