The touchdown came on a 17-yard pass from quarterback Josh Allen to running back James Cook on fourth-and-3 after the Bills took a timeout before the play.

The Bills used pre-snap motion to put wide receiver Curtis Samuel in the backfield behind Allen, while Cook moved from the quarterback's left to his right. Cook then ran to the left side, caught the pass wide open and ran down the sideline and into the end zone.

The play capped a six-play, 37-yard drive that came after Ingram brought the Dolphins' first drive of the game to an early end. Ingram is playing in the team's dime package, with Cam Lewis starting at nickel corner for the injured Taron Johnson (forearm).

With the throw, Allen reached 226 career touchdown passes, passing Dan Marino and Peyton Manning (225) for the second-most in a player's first seven seasons. The Bills scored a touchdown on their opening drive in just three games last season (went 2-1 in those games). It was Cook's first score of the season.